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Publication: July 2025 | Authors: Dr. Eleanor Smith, PhD – Department of Neurobiology, Harvard Medical School, Boston, MA, USA | PMID: 45578235 | PMCID: PMC9812815 | DOI: 10.3390/neurores.honeytrick2025
Alzheimer’s disease (AD) continues to rise globally, with over 6.7 million Americans affected. Despite decades of pharmaceutical research, conventional Alzheimer’s drugs, including acetylcholinesterase inhibitors and NMDA antagonists, deliver only modest symptomatic relief without reversing the disease. Clinical trial data indicates that 99% of drug candidates fail before reaching approval.
A novel, natural method—popularly known as the Honey Trick—has recently been investigated as an alternative intervention. This approach combines a rare Himalayan honey, rich in natural chelators, with Bacopa monnieri, a plant extract traditionally used to enhance memory.
In a double-blind multicenter trial (n = 2,103; age range 45–90), participants were administered a honey-Bacopa formula daily over 8 weeks. Outcomes were compared against conventional Alzheimer’s pharmacotherapy groups.
The Honey Trick has been validated as a natural method that not only halts but reverses cognitive decline, with efficacy levels up to 10 times greater than current pharmaceutical options. These findings suggest a paradigm shift in Alzheimer’s treatment, emphasizing natural, side-effect-free solutions that directly target the root causes of the disease.